Synthetic Tetrapeptide
Epitalon Research Tetrapeptide
Epitalon is a synthetic tetrapeptide with the sequence Ala-Glu-Asp-Gly (CAS 307297-39-8). It was originally developed as a synthetic analog of Epithalamin, a polypeptide extract derived from the pineal gland, and has been studied in preclinical models related to telomere biology and pineal gland function.
Compound identity
- Name
- Epitalon
- Class
- Synthetic Tetrapeptide
- CAS number
- 307297-39-8
- Molecular formula
- C14H22N4O9
- Also known as
- Epithalamin synthetic, Epitalamin, Ala-Glu-Asp-Gly tetrapeptide
- Sequence
- Ala-Glu-Asp-Gly
Research context
Epitalon (CAS 307297-39-8, molecular formula C14H22N4O9) is a tetrapeptide consisting of four amino acids: alanine, glutamic acid, aspartic acid, and glycine in sequence. It was developed by Vladimir Khavinson and colleagues at the St. Petersburg Institute of Bioregulation and Gerontology as a synthetic analog of Epithalamin, a natural pineal gland extract. The synthetic tetrapeptide has been studied in the context of pineal gland biology and circadian regulation research.
The primary research area associated with Epitalon involves telomere biology. Studies published by Khavinson's group have reported effects on telomerase activity and telomere length in preclinical models, including a study in human somatic cells demonstrating activation of telomerase (Regulatory Peptides, 2003). These findings have generated scientific interest, though the research base is relatively concentrated in a small number of groups and the methodology has been subject to varying levels of independent replication. Additional preclinical studies have examined effects on melatonin production in pineal gland models.
As a research reagent, Epitalon is used in studies examining telomere biology, circadian biology, and aging-related research models. DMV Research supplies Epitalon as a lyophilized powder with per-batch third-party Certificate of Analysis confirming identity (sequence confirmed by MS) and purity for research use.
Frequently asked questions
What is Epitalon?+
Epitalon is a synthetic tetrapeptide with the sequence Ala-Glu-Asp-Gly (CAS 307297-39-8). It was developed as a synthetic analog of Epithalamin, a pineal gland polypeptide, and has been studied in preclinical models related to telomere biology and circadian regulation.
What is the molecular structure of Epitalon?+
Epitalon consists of four amino acids: Alanine-Glutamic acid-Aspartic acid-Glycine (Ala-Glu-Asp-Gly). Molecular formula C14H22N4O9, molecular weight approximately 390.3 Da, CAS 307297-39-8.
Is Epitalon approved for human use?+
No. Epitalon is not approved for human use by the FDA or any other regulatory agency. As supplied by DMV Research, it is for laboratory and research purposes only.
What purity is the Epitalon research peptide?+
Each batch is independently tested to 99%+ purity by third-party laboratories, with a Certificate of Analysis confirming identity (mass spectrometry) and purity per batch.
Research use only
All products are intended for laboratory and research use only (RUO) and are not for human consumption, ingestion, or any in-vivo use.
The statements on this page have not been evaluated by the FDA. Epitalon is not intended to diagnose, treat, cure, or prevent any disease. Content is provided for laboratory research reference only.