GLP-1/GIP/Glucagon Receptor Triple Agonist
Retatrutide Research Peptide
Retatrutide is a synthetic peptide classified as a triple receptor agonist targeting the glucagon-like peptide-1 (GLP-1), glucose-dependent insulinotropic polypeptide (GIP), and glucagon receptors simultaneously. It is supplied as a lyophilized powder for laboratory research applications.
Compound identity
- Name
- Retatrutide
- Class
- GLP-1/GIP/Glucagon Receptor Triple Agonist
- CAS number
- 2381404-14-6
- Molecular formula
- C262H398N68O81
- Also known as
- LY3437943, GLP-1/GIP/Glucagon triagonist, GLP-3
Research context
Retatrutide (LY3437943, CAS 2381404-14-6) is a member of an emerging class of incretin-based research compounds. As a triple receptor agonist it is studied in preclinical models for its receptor-binding pharmacology across three metabolic signaling pathways.
The scientific literature on GLP-1/GIP/glucagon multi-agonists examines their receptor specificity and downstream signaling in in-vitro and animal-model systems. Phase-level clinical studies have been reported in peer-reviewed literature; the compound is not approved by the FDA or any regulatory agency for human therapeutic use.
DMV Research supplies Retatrutide with a per-batch third-party Certificate of Analysis confirming identity and purity for research use.
Frequently asked questions
What is Retatrutide?+
Retatrutide (LY3437943) is a synthetic peptide studied as a triple agonist at the GLP-1, GIP, and glucagon receptors. CAS 2381404-14-6. It is used as a research reference compound.
How does Retatrutide differ from GLP-1 agonists like semaglutide?+
Single GLP-1 agonists target only the GLP-1 receptor. Retatrutide is a triple agonist that also targets GIP and glucagon receptors, making it a structurally distinct research compound with different receptor pharmacology.
Is Retatrutide approved for human use?+
No. Retatrutide is not approved for human use by any regulatory agency. It is supplied for laboratory and research purposes only.
What purity is the Retatrutide research peptide?+
Each batch is independently tested to 99%+ purity by third-party laboratories, with a Certificate of Analysis available per batch.
Research use only
All products are intended for laboratory and research use only (RUO) and are not for human consumption, ingestion, or any in-vivo use.
The statements on this page have not been evaluated by the FDA. Retatrutide is not intended to diagnose, treat, cure, or prevent any disease. Content is provided for laboratory research reference only.