DSIP
Delta sleep-inducing peptide for sleep research.
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For in-vitro and pre-clinical research use only. Not for human consumption, therapeutic use, or veterinary application. Research Use Only Policy
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Compound Information
Updated 2026-06-08Technical specifications
Delta sleep-inducing peptide — a nonapeptide first isolated from rabbit cerebral venous blood in 1977 by Schoenenberger and Monnier. Assigned the INN name emideltide. Studied in chronobiology, stress-response, pain research, and neuroendocrine research models.
What Is DSIP?
- Type
- Endogenous Nonapeptide
- CAS Number
- 62568-57-4
- Molecular Weight
- 848.8 g/mol
- Molecular Formula
- C₃₅H₄₈N₁₀O₁₅
- Amino Acids
- 9
- Sequence
- Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu
- Primary Target
- Multiple neuromodulatory systems (research context)
Stability Information
Lyophilized (powder)
-20°C· stable
Reconstituted
2–8°C· use within 24 hours
Neuromodulatory Signaling
Stress axis and sleep-wake regulation
Research Outcomes
Sources & References
9 sources · research references
Journal of Neurochemistry
Delta Sleep-Inducing Peptide (DSIP): A Still Unresolved Riddle
2006
Kovalzon VM, Strekalova TV
Neuroscience & Biobehavioral Reviews
Delta-Sleep-Inducing Peptide (DSIP): A Review
1984
Graf MV, Kastin AJ
Peptides
Delta-Sleep-Inducing Peptide (DSIP): An Update
1986
Graf MV, Kastin AJ
Neuropsychobiology
Effects of Delta Sleep-Inducing Peptide on Sleep of Chronic Insomniac Patients
1992
Bes F, Hofman W, van Ommen J, van Leusen B, Dijk DJ, Beersma D
International Journal of Clinical Pharmacology
Acute and Delayed Effects of DSIP on Human Sleep Behavior
1981
Schneider-Helmert D, Gnirss F, Monnier M, Schenker J, Schoenenberger GA
European Neurology
DSIP in the Treatment of Withdrawal Syndromes from Alcohol and Opioids
1984
Dick P, Grandjean ME, Tissot R
European Neurology
Therapeutic Effects of Delta-Sleep-Inducing Peptide in Patients with Chronic, Pronounced Pain Episodes
1984
Larbig W, Gerber WD, Kluck M, Schoenenberger GA
Molecules
Delta Sleep-Inducing Peptide Recovers Motor Function and Reduces Oxidative Stress in a Mouse Model
2021
Tukhovskaya EA, Kulikov AN, Khokhlova ON, et al.
PubChem Database
DSIP Compound Information
Not for human consumption. This product is sold exclusively for research and educational purposes. It is not intended to diagnose, treat, cure, or prevent any disease.
All clinical trial data and research findings presented on this page are sourced from peer-reviewed journals and official publications. They are provided for educational reference only and should not be interpreted as medical advice or product claims.
By purchasing this product, you confirm that you are a qualified researcher and will use it in accordance with all applicable laws and regulations. See our Research Use Only policy.
