GHK-Cu
Copper peptide complex for skin and tissue research.
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For in-vitro and pre-clinical research use only. Not for human consumption, therapeutic use, or veterinary application. Research Use Only Policy
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Compound Information
Updated 2026-06-08Technical specifications
A copper-binding tripeptide (glycyl-histidyl-lysine) that forms a stable 1:1 complex with copper(II). Naturally present in human plasma; concentration declines with age. Studied in dermal-biology and extracellular-matrix research for copper-dependent enzymatic pathways.
What Is GHK-Cu?
- Type
- Copper-Binding Tripeptide
- Molecular Weight
- 340.4 g/mol (free peptide) / 402.9 g/mol (copper complex)
- Molecular Formula
- C₁₄H₂₄N₆O₄ (free peptide) / C₁₄H₂₂CuN₆O₄ (copper complex)
- Amino Acids
- 3
- Sequence
- Gly-His-Lys
- Primary Target
- Copper-dependent enzymes, extracellular matrix proteins, collagen synthesis
Stability Information
Lyophilized (powder)
-20°C· stable
Reconstituted
2–8°C· use within 30 days
Copper-Dependent ECM Signaling
Collagen synthesis and antioxidant pathways
Research Outcomes
Sources & References
9 sources · research references
Aging Pathobiology and Therapeutics
The Potential of GHK as an Anti-Aging Peptide
2020
Dou Y, et al.
BioMed Research International
GHK Peptide as a Natural Modulator of Multiple Cellular Pathways in Skin Regeneration
2015
Pickart L, Vasquez-Soltero JM, Margolina A
Journal of Biomaterials Science
The Human Tri-Peptide GHK and Tissue Remodeling
2008
Pickart L
Oxidative Medicine and Cellular Longevity
The Human Tripeptide GHK-Cu in Prevention of Oxidative Stress and Degenerative Conditions of Aging
2012
Pickart L, Vasquez-Soltero JM, Margolina A
Pharmaceutics
Liposomes as Carriers of GHK-Cu Tripeptide for Cosmetic Application
2023
Dymek M, et al.
Journal of Cosmetic Science
Effect of a Copper Peptide Complex on Healing of Wounds in Normal and Impaired Mice
2005
Finkley MB, et al.
Journal of Cosmetic and Laser Therapy
A Split-Face Study Examining the Effect of a Topical Product Containing Copper Tripeptide-1
2007
Appa Y
International Journal of Dermatology
Topical Peptides as Cosmeceuticals
2009
Gorouhi F, Maibach HI
PubChem Database
GHK-Cu Compound Information
Not for human consumption. This product is sold exclusively for research and educational purposes. It is not intended to diagnose, treat, cure, or prevent any disease.
All clinical trial data and research findings presented on this page are sourced from peer-reviewed journals and official publications. They are provided for educational reference only and should not be interpreted as medical advice or product claims.
By purchasing this product, you confirm that you are a qualified researcher and will use it in accordance with all applicable laws and regulations. See our Research Use Only policy.
