NAD+
Nicotinamide adenine dinucleotide for cellular energy research.
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Compound Information
Updated 2026-06-08Technical specifications
Nicotinamide adenine dinucleotide — a fundamental coenzyme present in all living cells. Functions as an electron carrier in cellular metabolism and as a substrate for sirtuin deacetylases and PARP enzymes involved in DNA repair.
What Is NAD+?
- Type
- Coenzyme / Nucleotide
- CAS Number
- 53-84-9
- Molecular Weight
- 664.4 g/mol
- Molecular Formula
- C₂₁H₂₇N₇O₁₄P₂
- Amino Acids
- N/A (nucleotide)
- Primary Target
- Sirtuins (SIRT1–7), PARPs, CD38, NAMPT
Stability Information
Lyophilized (powder)
-20°C· stable
Reconstituted
2–8°C· use within 7 days
NAD⁺ Metabolic Hub
Coenzyme and sirtuin substrate
Research Outcomes
Sources & References
9 sources · research references
Cold Spring Harbor Perspectives in Medicine
Roles of NAD+ in Health and Aging
2024
Lautrup S, et al.
Circulation
NAD+ Metabolism in Cardiac Health, Aging, and Disease
2021
Abdellatif M, Sedej S, Kroemer G
Cell Metabolism
NAD+ Intermediates: The Biology and Therapeutic Potential of NMN and NR
2018
Yoshino J, Baur JA, Imai SI
Subcellular Biochemistry
NAD+ Boosting Strategies
2024
Rice J, Lautrup S, Fang EF
Frontiers in Endocrinology
NAD+ and Its Metabolites as Novel Biomarkers of Aging and Age-Related Disease
2022
Yang F, et al.
Trends in Cell Biology
NAD+ and Sirtuins in Aging and Disease
2014
Imai S, Guarente L
Antioxidants
Prolonged Nicotinamide Administration Influences Sirtuin Activity and Intracellular NAD+ Levels
2019
Grant R, et al.
Circulation Research
Sirtuins and NAD+ in the Development and Treatment of Metabolic and Cardiovascular Disease
2018
Kane AE, Sinclair DA
PubChem Database
NAD+ Compound Information
Not for human consumption. This product is sold exclusively for research and educational purposes. It is not intended to diagnose, treat, cure, or prevent any disease.
All clinical trial data and research findings presented on this page are sourced from peer-reviewed journals and official publications. They are provided for educational reference only and should not be interpreted as medical advice or product claims.
By purchasing this product, you confirm that you are a qualified researcher and will use it in accordance with all applicable laws and regulations. See our Research Use Only policy.
