
Ipamorelin
Selective growth hormone secretagogue for GH research.
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For in-vitro and pre-clinical research use only. Not for human consumption, therapeutic use, or veterinary application. Research Use Only Policy
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Compound Information
Updated 2026-06-08Technical specifications
A selective ghrelin-receptor (GHS-R1a) agonist and pentapeptide growth-hormone secretagogue. Distinguished in research for its selectivity profile — minimal cortisol or prolactin response compared to other secretagogues.
What Is Ipamorelin?
- Type
- Synthetic Pentapeptide (GHS-R1a Agonist)
- CAS Number
- 170851-70-4
- Molecular Weight
- 711.9 g/mol
- Molecular Formula
- C₃₈H₄₉N₉O₅
- Amino Acids
- 5
- Sequence
- Aib-His-D-2-Nal-D-Phe-Lys-NH₂
- Primary Target
- GHS-R1a (ghrelin receptor)
Stability Information
Lyophilized (powder)
-20°C· stable
Reconstituted
2–8°C· use within 30 days
GHS-R1a Selective Agonism
GH secretagogue without ACTH/cortisol response
Research Outcomes
Dosing in Clinical Studies
Protocols from published peer-reviewed trials. Provided for educational reference only — not prescribing guidance.
| Protocol | Dose | Route | Frequency | Indication (Research) |
|---|---|---|---|---|
| Phase 2 Postoperative Ileus Trial (Beck et al.) | 0.01 mg/kg | Intravenous (IV) infusion | Three times daily (TID) starting 3–6 hours post-surgery | Postoperative GI motility research model |
Sources & References
8 sources · research references
European Journal of Endocrinology
Ipamorelin, the First Selective Growth Hormone Secretagogue
1998
Raun K, et al.
British Journal of Pharmacology
Pharmacokinetic and Pharmacodynamic Study of Ipamorelin: A New Growth Hormone Releasing Peptide
1999
Johansen PB, Segev Y, Landau D, et al.
Growth Hormone & IGF Research
The Growth Hormone Secretagogue Ipamorelin Counteracts Glucocorticoid-Induced Decrease in Bone Formation
2001
Andersen NB, et al.
Journal of Gastrointestinal Surgery
Ipamorelin Reduces Postoperative Ileus in Gastrointestinal Surgery: A Phase 2 Randomized Controlled Trial
2014
Beck DE, Sweeney WB, McCarter MD
Journal of Pharmacology and Experimental Therapeutics
Efficacy of Ipamorelin, a Novel Ghrelin Mimetic, in a Rodent Model of Postoperative Ileus
2009
Venkova K, et al.
Sexual Medicine Reviews
The Safety and Efficacy of Growth Hormone Secretagogues
2018
Sigalos JT, Pastuszak AW
Physiology & Behavior
GHS-R1a Agonists Anamorelin and Ipamorelin Inhibit Cisplatin-Induced Weight Loss in Ferrets
2024
Lu Z, et al.
PubChem Database
Ipamorelin Compound Information
Not for human consumption. This product is sold exclusively for research and educational purposes. It is not intended to diagnose, treat, cure, or prevent any disease.
All clinical trial data and research findings presented on this page are sourced from peer-reviewed journals and official publications. They are provided for educational reference only and should not be interpreted as medical advice or product claims.
By purchasing this product, you confirm that you are a qualified researcher and will use it in accordance with all applicable laws and regulations. See our Research Use Only policy.




