Selank
Synthetic analog of tuftsin for anxiolytic research.
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For in-vitro and pre-clinical research use only. Not for human consumption, therapeutic use, or veterinary application. Research Use Only Policy
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Compound Information
Updated 2026-06-08Technical specifications
A synthetic heptapeptide analog of the immunomodulatory peptide tuftsin, with a Pro-Gly-Pro C-terminal stabilizing extension. Studied in neurochemistry research for GABAergic modulation and anxiolytic mechanisms.
What Is Selank?
- Type
- Synthetic Heptapeptide (Tuftsin Analog)
- CAS Number
- 129954-34-3
- Molecular Weight
- 751.9 g/mol
- Molecular Formula
- C₃₃H₅₇N₁₁O₉
- Amino Acids
- 7
- Sequence
- Thr-Lys-Pro-Arg-Pro-Gly-Pro
- Primary Target
- GABAergic system, serotonin transporters, BDNF
Stability Information
Lyophilized (powder)
-20°C· stable
Reconstituted
2–8°C· use within 30 days
GABAergic Modulation
Anxiolytic and immunomodulatory pathways
Research Outcomes
Dosing in Clinical Studies
Protocols from published peer-reviewed trials. Provided for educational reference only — not prescribing guidance.
| Protocol | Dose | Route | Frequency | Indication (Research) |
|---|---|---|---|---|
| Generalized Anxiety Disorder Trial (Zozulia 2008) | 250–500 mcg per nostril | Intranasal | 2–3 times daily for 14 days | Generalized anxiety disorder research model |
Sources & References
9 sources · research references
Zhurnal Nevrologii i Psikhiatrii im. S.S. Korsakova
The Neuropeptide Selank as an Anxiolytic Agent: Results of a Controlled Clinical Trial in Patients with Generalized Anxiety Disorder
2008
Zozulia AA, et al.
Bulletin of Experimental Biology and Medicine
Selank Peptide Modulates Cytokine Profile in Rats Under Conditions of Emotional Stress
2020
Vyunova TV, et al.
Behavioural Neurology
Selank Prevents Memory Deficits and Reduces Oxidative Stress in Transgenic Alzheimer Mice
2017
Kasian A, et al.
Frontiers in Pharmacology
Tuftsin Analogue Selank Regulates Gene Expression of Cytokines and Their Receptors in Rat Immunocompetent Cells
2016
Volkova A, et al.
Neuroscience and Behavioral Physiology
Selank and Short Peptides of the Tuftsin Family in the Regulation of Adaptive Behavior in Stress
2003
Kozlovskaya MM, et al.
Bulletin of Experimental Biology and Medicine
Inhibitory Effect of Selank on Enkephalin-Degrading Enzymes as a Possible Mechanism of Its Anxiolytic Activity
2001
Zozulya AA, et al.
Bulletin of Experimental Biology and Medicine
Selank Protects Against Ethanol-Induced Memory Impairment by Regulating BDNF Content
2019
Kolik LG, et al.
Bulletin of Experimental Biology and Medicine
Selank Attenuates Aversive Signs of Morphine Withdrawal in Rats
2022
Konstantinopolsky MA, et al.
PubChem Database
Selank Compound Information
Not for human consumption. This product is sold exclusively for research and educational purposes. It is not intended to diagnose, treat, cure, or prevent any disease.
All clinical trial data and research findings presented on this page are sourced from peer-reviewed journals and official publications. They are provided for educational reference only and should not be interpreted as medical advice or product claims.
By purchasing this product, you confirm that you are a qualified researcher and will use it in accordance with all applicable laws and regulations. See our Research Use Only policy.
